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Special Issue "Molecular Mechanisms of Bioactive Nutrients Promoting Health through Gut Microbiota 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 28 February 2022.

Special Issue Editors

Dr. Matteo Bordiga
E-Mail Website
Guest Editor
Department of Pharmaceutical Sciences, University of Piemonte Orientale (UPO), Largo Donegani 2, Novara, Italy
Interests: food chemistry; gas chromatography; liquid chromatography; mass spectrometry; polyphenols; volatile compounds; wine chemistry; extraction; fermentation; prebiotic compounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is becoming clear that human gut microbiota plays a critical role in human health. The human gut microbiota, depending on dietary intake and consequently nutrient availability within the gut, can produce either harmful metabolite led to human diseases or beneficial compounds that protect against host diseases.  Abnormal gut microbiota can produce endotoxins, which enhance the chronic inflammation and metabolic disorders. Modification of gut microbiota by bioactive food components to balance its compositions becomes a promising strategy to help manage colon health and host health. Bioactive components obtained from dietary source which are designed and characterized to meet human nutritional and immunological needs as well as balance the gut microbiota. The goal of this special issue is to collect the latest research findings on the interrelationship among bioactive food components (such as phytochemicals and complex carbohydrates), gut microbiota, colon stem cells, and chronic metabolic diseases. Health benefits of small molecular phytochemicals and large biopolymer polysaccharides have been reported in different disciplines; however it is not clear that how gut microbiota metabolize these dietary phytochemicals and polymers; it is also not clear that how the gut metabolites from these dietary compounds further affect.

Prof. Dr. Baojun Xu
Dr. Matteo Bordiga
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • phytochemicals
  • complex carbohydrates
  • bioactive nutrients
  • gut microbiota
  • prebiotics
  • probiotics
  • inflammation
  • molecular mechanisms
  • human health

Published Papers (1 paper)

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Review

Review
An Insight into Anti-Inflammatory Activities and Inflammation Related Diseases of Anthocyanins: A Review of Both In Vivo and In Vitro Investigations
Int. J. Mol. Sci. 2021, 22(20), 11076; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms222011076 - 14 Oct 2021
Viewed by 207
Abstract
Anthocyanin is a type of flavonoid pigment widely present in fruits and vegetables. It can not only be used as natural pigment, but also has a variety of health functions, for instance, anti-oxidant, anti-inflammatory, anti-tumor, and neuroprotective activities. Persistent proinflammatory status is a [...] Read more.
Anthocyanin is a type of flavonoid pigment widely present in fruits and vegetables. It can not only be used as natural pigment, but also has a variety of health functions, for instance, anti-oxidant, anti-inflammatory, anti-tumor, and neuroprotective activities. Persistent proinflammatory status is a major factor in the development, progression, and complications of chronic diseases. Not surprisingly, there are thus many food ingredients that can potentially affect inflammation related diseases and many studies have shown that anthocyanins play an important role in inflammatory pathways. In this paper, the inflammation related diseases (such as, obesity, diabetes, cardiovascular disease, and cancer) of anthocyanins are introduced, and the anti-inflammatory effect of anthocyanins is emphatically introduced. Moreover, the anti-inflammatory mechanism of anthocyanins is elaborated from the aspects of NF-κB, toll like receptor, MAPKs, NO, and ROS and the main efficacy of anthocyanins in inflammation and related diseases is determined. In conclusion, this review aims to get a clear insight into the role of anthocyanins in inflammation related diseases. Full article
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