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Special Issue "Immunophenotyping in Autoimmune Diseases and Cancer 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 31 January 2022.

Special Issue Editors

Dr. Gabor J. Szebeni
E-Mail Website
Guest Editor
Biological Research Centre, Temesvári krt. 62, H-6726 Szeged, Hungary
Interests: antitumor immunity; inflammation; phenotypic screening in drug development; single cell mass cytometry; flow cytometry applications
Special Issues and Collections in MDPI journals
Dr. László G. Puskás
E-Mail Website
Guest Editor
Biological Research Centre, Temesvári krt. 62, H-6726 Szeged, Hungary
Interests: immuno-oncology; in vitro diagnostics; single cell genomics; microarray technologies
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

The mammalian immune system is a Janus-faced network of well-coordinated, highly specialized cells and biomolecules. The sensitive balance of reactive and suppressive signals maintains homeostasis in the physiological state. Under pathological conditions, however, responsiveness can escalate in autoimmune diseases or remain suppressed in cancer. In severe autoimmunity, the overwhelming immune response leads to devastating diseases, such as rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis, sclerosis multiplex, etc. Conversely, immune cells, e.g., professional antigen-presenting cells and cytotoxic T cells, are not able to execute their physiological function in cancer.

Recent progress in fluorescence flow cytometry and mass cytometry has contributed to a high-dimensional resolution of the complex immunophenotype, both in autoimmune diseases and in cancer. We would like to call authors to publish their latest achievements associated with the perturbance of the regulation of immune activation and the discovery of rare subpopulations of both innate and adaptive immune players in autoimmune diseases or cancer. This Special Issue will publish works presenting not only the description of different cellular subtypes but also the identification of novel key molecular factors and biomarkers. Submission of mainly research articles is expected. Due to the recent developments in high-content, multilevel profiling technologies, review articles from pioneer scientists will also be considered.

Dr. Gabor J. Szebeni
Dr. László G. Puskás
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • immunophenotyping
  • immune regulation
  • multiparameter cytometry
  • immuno-oncology
  • anti-tumor immunity
  • autoimmunity
  • cancer immunology

Published Papers

This special issue is now open for submission.
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