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Special Issue "Host Infectomics in the Childhood 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".

Deadline for manuscript submissions: 31 October 2021.

Special Issue Editor

Prof. Dr. Antonio Salas
E-Mail Website
Guest Editor
Departamento de Anatomía Patolóxica e Ciencias Forenses, Instituto de Ciencias Forenses, Facultade de Medicina, University of Santiago de Compostela, Galicia, Spain
Interests: genetics; genomics; transcriptomics; epigenomics; exomes; complete genomes; exomes; ultrasequencing; NGS; DNA polymorphisms; single nucleotide polymorphism; SNP; short tandem repeat; STR; autosomes; complex multifactorial diseases; rare diseases; population genetics; evolutionary genetics
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Special Issue Information

Dear Colleagues,

Despite the availability of new vaccines and antibacterial agents suppressing microbial pathogens, infectious diseases are among the leading cause of morbidity and mortality worldwide. While there are a number of studies dealing with infections in adults (mainly focused on some particular diseases, e.g., tuberculosis) and/or pathogens, less attention has been devoted to the pediatric age. To overcome this deficiency, several international consortia have emerged in the last decade aimed at investigating life-threatening infections affecting childhood.

‘Omic’ sciences are gaining growing attention in parallel with the development of new and cost-effective technologies, but also bioinformatic and mathematical solutions that allow dealing with big data from massive genotyping and sequencing technologies. The field of infectiology is one of the many in biomedicine that is benefiting from these new achievements, and in particular, the area studying host response to infection from different ‘omic’ perspectives, namely, host infectomics. Thus, there is now increasing evidence supporting that it is not only the pathogen that decides how and when to infect the host, but also the biological predisposition of the host to be infected by the pathogen. Most of the genomic studies published to date have focused their attention on genomics, first by exploring a few thousands of single nucleotide polymorphisms (SNPs) distributed throughout the whole genome in large case-control samples (e.g., population-based genome-wide association studies; GWAS), and more recently using parallel sequencing procedures (e.g., whole exome sequencing, WES). There are also interesting attempts in the terrain of transcriptomic, using microarrays and more recently RNAseq, to investigate the host genetic expression response to different infections and pathogens.

We invite researchers to contribute original research articles and reviews focused on host infectomics in children. Topics of interest include but are not limited to the following:

  • Genomics, transcriptomics, epigenomics, proteomics, etc.;
  • Systems biology;
  • Studies exploring big data resources and using discovery-based procedures and providing insights on host biomarkers for infections.

Prof. Dr. Antonio Salas
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

This special issue is now open for submission.
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