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Special Issue "The Interplay between Innate and Adaptive Immunity in Autoimmune Disorders"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 30 November 2021.

Special Issue Editor

Dr. Violetta Opoka-Winiarska
E-Mail Website
Guest Editor
Department of Paediatric Pulmonology and Rheumatology, Medical University of Lublin, 20-093 Lublin, Poland
Interests: rheumatology; immunology; autoimmune; autoinflammatory disorders

Special Issue Information

Dear Colleagues,

In recent years, advances in understanding the pathomechanisms of autoimmune diseases have led to new therapy pathways with great benefits for patients. Nevertheless, the trigger factors and mechanisms affecting the disease development, its activity, and response to therapy remain unknown.

The key mechanism of autoimmune disorder is loss of immune tolerance against self-antigens, leading to unregulated immune activation and tissue damage. These disorders affect different types of components of the immune response, including innate and adaptive immune cells, cytokines, and complements . A better understanding of the mechanisms underlying the development of autoimmune diseases is essential for the development of new diagnostic methods, markers of disease activity, and specific treatments.

The aim of this Special Issue is to present the current progress in autoimmune diseases include but not limited to rheumatic diseases. Please note that the IJMS provides a forum for the publication of molecular research in biology and chemistry, with a strong focus on molecular biology and molecular medicine.  Therefore, clinical observations should be directed to other journals.

Dr. Violetta Opoka-Winiarska
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • rheumatic diseases
  • autoimmune diseases
  • trigger factors
  • immune tolerance
  • self-antigens
  • components
  • cytokines
  • complements

Published Papers

This special issue is now open for submission.
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