Special Issue "Intercellular Communication in Cancer"
Deadline for manuscript submissions: 31 March 2022.
Interests: Intercellular communication; Cancer; Ephrins; Connexins; Apoptosis; Autophagy; Intracellular trafficking; Receptor tyrosine kinases
Special Issues and Collections in MDPI journals
It goes without saying that multicellular organisms are “social” entities, and that intercellular communication is a sine qua non condition for tissue homeostasis during organism development and for proper biological functioning of tissues. This means that cells are intricately interdependent at the deepest molecular levels. In addition to responding to signaling cues received from their acellular microenvironment, be it the extracellular matrix or fluidic streams, among others, they “listen” to other cells, whether via direct membrane-based cell–cell contacts or via factors released in the milieu. Intercellular communication is thus, understandably, key to comprehending all normal and pathological processes.
In this Special Issue of IJMS, I am pleased to invite manuscripts reporting data that focus on how molecular dysfunction in different types of intercellular communications, i.e., direct membrane-based interactions between cells (gap, tight, adherens, etc.), exosomes and other vesicular structures, tunneling nanotubes, Ephrins, Semaphorins, growth factors and receptors, etc., can contribute to cancer development, progression, and drug resistance, and how specific therapeutic strategies could be developed to take aim at these communication devices. Our aim is to reflect on the extent to which different communication processes result in distinct molecular wirings of cancer-prone, cancerous cells or drug-resistant cells. In particular, we believe that it is of great importance to compare direct membrane-based cell–cell contacts to released factor-based contactless communication.
Dr. Mustapha Kandouz
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- intercellular communication
- cell–cell communication
- growth factors
- cancer therapy
- cancer resistance