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Special Issue "Molecular Mechanisms Employed by Neurons to Receive and Transduce Signals Essential for Learning and Memory"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editors

Prof. Dr. Efthimios M.C. Skoulakis
E-Mail Website
Guest Editor
Institute for Fundamental Biomedical Research, Biomedical Sciences Research Centre "Alexander Fleming”, Vari Greece
Interests: Mechanisms of Habituation; Associative Learning and Memory in Drosophila and mice. Pharmacogenetics of neurodegenerative tauopathies; learning disabilities and psychiatric conditions in Drosophila models
Prof. Dr. Antonis Stamatakis
E-Mail Website
Guest Editor
Biology-Biochemistry lab, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, Greece
Interests: behavioural neuroscience; behaviour (using rodents as experimental animals); mechanisms of learning and memory, maternal behaviour, sex differences in stress responses, epigenetic effects of early life experiences on neonatal and adult brain structure

Special Issue Information

Dear Colleagues,

Learning and memory are sub-served by distinct processes, such as encoding, consolidation storage, retrieval and modulation of the mnemonic engram. Although the cellular and molecular events underlying these processes have been extensively studied, the precise mechanisms differentiating them and the neural codes employed are currently, at best, fragmentary.

The circuitry and molecular mechanisms potentially differentially engaged, and hence characterizing distinct types of learning and memory forms (e.g., episodic, emotional, procedural, working, non-associative), are little understood to date. The role of neuronal population oscillatory dynamics, the orchestration of activities of different neurotransmitters and neuromodulators—including the effects of stress or gonadal hormones—the intracellular signaling pathways engaged, or the epigenetic and epitranscriptomic modifications imposed by learning and being connected with memory are intensely studied, but much remains unexplored.

We invite contributions of original research papers, computational models, and reviews, as well as position/theoretical papers. Studies combining experimental approaches, including genetic/epigenetic interventions, cellular, biochemical, molecular, –omics analyses, optogenetic manipulations or behavioral assays, are encouraged. Reviews and position/theoretical papers addressing their themes in a comparative approach, across memory types, neuronal modalities or experimental species, are welcome.

Prof. Efthimios M.C. Skoulakis
Prof. Dr. Antonis Stamatakis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • learning
  • memory
  • neuronal
  • neurotransmitters
  • neuromodulators
  • epigenetic
  • epitranscriptomic modifications

Published Papers

This special issue is now open for submission.
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