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Special Issue "Role of Lipids in Cancer"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editors

Dr. Angela Maria Rizzo
E-Mail Website
Guest Editor
Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy
Interests: lipid biochemistry; lipidomics; Omega-3; cancer biology; applied nutrition; space life sciences
Dr. Paola Antonia Corsetto
E-Mail Website
Guest Editor
Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milan, Italy
Interests: lipid metabolism; inflammation; cancer biology

Special Issue Information

Dear Colleagues,

Lipids are a heterogeneous class of biomolecules which altered metabolism is one of the key features of cancer, relevant for development, chemotherapy and immunotherapy. Indeed, lipids modulate cell signaling through the lipid–protein and lipid–lipid interactions and membrane dynamics; increasing lipid content promotes cell proliferation, tumor progression, and chemotherapy resistance and fatty acids are needed for energy storage, membrane structure, and precursors of signaling molecules. Most of the enzymes and carriers involved in lipid procurement and synthesis are abnormally expressed in cancer cells and in some conditions their chemical and genetic inhibition effects cancer viability and immune response. Therefore, this Special Issue will describe recent advances in the understanding of the role of lipids and their metabolites on cancer progression and therapy success. For this aim, we will present studies that highlight the impact of peculiar lipid phenotype on cancer progression and immune cell phenotyping. In addition, this Special Issue could be an opportunity to present new molecular and/or cellular mechanisms of action of lipids and to propose new targets to ameliorate the anticancer strategies.

Dr. Angela Maria Rizzo
Dr. Paola Antonia Corsetto
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lipid
  • lipid metabolism
  • tumor progression
  • immunotherapy
  • lipid–protein interactions
  • fatty acids

Published Papers

This special issue is now open for submission.
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