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Special Issue "Macrophages in Immunotherapy"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 31 March 2022.

Special Issue Editors

Dr. Larisa Kuznetsova
E-Mail Website
Guest Editor
Institute of General Pathology and Pathophysiology, Moscow State University of Medicine and Dentistry, Baltijskaya Street 8, Moscow 125315, Russia
Interests: immunotherapy; biotechnology; adoptive cell transfer; macrophages; ex vivo cell reprogramming; solid tumour; ex vivo tumour models
Special Issues and Collections in MDPI journals
Prof. Dr. Igor Y. Malyshev
E-Mail Website
Guest Editor
Institute of General Pathology and Pathophysiology, Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Baltijskaya Street 8, Moscow 125315, Russia
Interests: immunotherapy; biotechnology; adoptive cell transfer; macrophages; ex vivo cell reprogramming; solid tumour; ex vivo tumour models
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Immunotherapy refers to treating diseases by activating or suppressing one's immune system, introducing immune products or reprogramming and modifying immune cells into the body. Macrophages play a crucial role in recognizing a pathogenic agent and initiating an immune response. The therapeutic efficiency of the immune system critically depends on how adequately macrophages perceive signals from microbes, damaged and transformed cells, and how they present antigens and promote the activation of lymphocytes. In order to fully utilize the potential of macrophages in immunotherapy, it is necessary to understand well:

  1. The role of macrophages in various diseases;
  2. Mechanisms of perception of pathogenic factors and stimuli by macrophages and responses in the form of inflammatory, anti-inflammatory, angiogenic or reparative response;
  3. What mechanisms of presentation macrophages use and how they help the development of an antigen-specific response;
  4. What mechanisms of the immune response, impaired by the disease, can restore macrophages, and what modifications of macrophages can enhance the therapeutic potential of these cells. This Special Issue will be dedicated to the current knowledge available on these issues, with a primary focus of interest on macrophage-centered approaches to anticancer, antimicrobial and anti-inflammatory immunotherapy. We welcome contributions in the form of original research articles and reviews.

Dr. Larisa Kuznetsova
Prof. Dr. Igor Malyshev
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • macrophages
  • immunotherapy
  • adoptive cell transfer
  • ex vivo macrophage reprogramming
  • macrophage-based presentation

Published Papers

This special issue is now open for submission.
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