Special Issue "Signaling Systems in Membrane-Associated Proteins"
Deadline for manuscript submissions: 30 November 2021.
Interests: cell behavior; calcium signals; membrane-associated proteins; membrane properties; G protein signaling
Special Issues and Collections in MDPI journals
Biological membranes regulate communication between the external environment and internal compartments. Aside from serving as a barrier, the structure and content of the membrane itself plays a critical role in generating and propagating cellular signals. This issue examines the series of events that occur when extracellular information is received by plasma membrane and how this information generates various cascades of association/dissociation reactions between signaling molecules that lead to specific intracellular events. Changes in these protein interactions, along with concurrent intracellular signals, allow cells to proliferate, divide, migrate, and/or undergo morphological changes. The articles in this issue focus on signals occurring on the plasma and internal membranes that include enzymes that generate soluble second messengers, such as inositol phosphates, cAMP and Ca2+, as well as insoluble second messengers, such as diacylglycerol and phosphatidylinositide 4,5 bisphosphate. Articles will range from the interfacial association between proteins and the membrane surface that drive enzyme reaction dynamics to how cell membranes promote associations between peripheral proteins. Generation and enhancement of lipid signals and discussion of the properties specific to lipid modifying enzymes will be included. Importantly, the ability of these enzymes to communicate with associated signaling networks to drive cell function under normal and transformed conditions will be highlighted.
Prof. Dr. Suzanne Scarlata
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- lipid membranes
- lipid-modifying enzymes
- membrane organization
- interfacial activation
- signaling complexes