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Special Issue "New Approaches for the Management of Metabolic Syndrome and Related Health Alterations: A Focus in Probiotics, Parabiotics and Postbiotics"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 31 March 2022.

Special Issue Editors

Dr. Iñaki Milton-Laskibar
E-Mail Website
Guest Editor
1. Cardiometabolic Nutrition Group, IMDEA Food Institute, 28049 Madrid, Spain
2. CIBER Fisiopatología Obesidad y Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain
Interests: obesity; diabetes; NAFLD; lipid metabolism; autophagy; mitochondria; polyphenols
Special Issues and Collections in MDPI journals
Prof. Dr. María P. Portillo
E-Mail Website1 Website2
Guest Editor
Nutrition and Obesity Group, Department of Nutrition and Food Science, Faculty of Pharmacy and Lucio Lascaray Research Center, University of the Basque Country (UPV/EHU), Vitoria, Spain
CIBER Fisiopatología Obesidad y Nutrición, Instituto de Salud Carlos III, Madrid, Spain.BIOARABA Institute of Health, Vitoria-Gasteiz, Spain
Interests: obesity; liver steatosis; insulin resistance; bioactive compounds; mitochondria; autophagy
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Metabolic syndrome is a health condition in which several risk factors, such as increased waist circumference, high fasting blood glucose, arterial hypertension, and dyslipidemia (increased blood triglyceride and decreased HDL cholesterol levels) occur simultaneously, enhancing the risk of heart disease, stroke, diabetes, or atherosclerosis. Moreover, the aforementioned risk factors can also derive metabolic diseases such as obesity or diabetes, which like metabolic syndrome may increase the risk of developing further health impairments. Indeed, metabolic syndrome and related health alterations are not only among the most prevalent non-communicable diseases in Western societies, but are also considered the main causes of early death. Despite the importance and high prevalence of these health alterations, their treatment is usually based in lifestyle modification informed by dietary advice and physical activity programs, which in turn show limited success due to low adherence.

In this scenario, the scientific community is constantly looking for bioactive compounds that may exert potential benefits and thus result as useful tools for the prevention or treatment of metabolic syndrome and related health alterations. In this regard, due to the involvement of gut microbiota in the development of the aforementioned impairments, the usage of probiotics, which is common for other conditions such as constipation, has been proposed. However, since the use of probiotics implies the administration of viable bacteria, a great deal of attention has recently been paid to parabiotics (non-viable microorganisms) and postbiotics (metabolites produced by probiotic bacteria) as potential alternative approaches.

This Special Issue aims to provide up-to-date information regarding the current knowledge and research in the use of probiotics, parabiotics, and postbiotics in the prevention and treatment of metabolic syndrome and related health alterations. Authors are invited to contribute current original research (molecule-level study or preclinical studies) as well as review articles.

Dr. Iñaki Milton-Laskibar
Prof. Dr. María P. Portillo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • metabolic syndrome
  • obesity
  • diabetes
  • microbiota
  • probiotics

Published Papers

This special issue is now open for submission.
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