Special Issue "Molecular Mechanisms, Pathophysiology and Phenotypes of Mitochondrial Disorders"
Deadline for manuscript submissions: 30 September 2021.
Mitochondrial diseases are the most common inheritable metabolic diseases resulting from defects in oxidative phosphorylation. They are caused by mutations of nuclear or mitochondrial DNA in genes involved in mitochondrial function. While some mitochondrial disorders only affect a single organ (e.g., the eye in Leber hereditary optic neuropathy), many involve multiple organ systems and often present with prominent neurologic features. Understanding the phenotypic diversity and elucidating the molecular mechanisms at the basis of these diseases has, however, proved challenging.
With this Special Issue, we intent to explore the molecular basis, the clinical spectrum, the diagnostic approach and the treatment advances of these devastating disorders.
Prof. Dr. michelangelo mancuso
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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- mitochondrial diseases
- clinical phenotypes
- diagnostic approaches