Special Issue "Molecular Immunology in Hematological Disorders"
Deadline for manuscript submissions: 28 February 2022.
Interests: hematopoietic stem cell transplantation; functional genetics; molecular immunobiology; NK cells; laboratory hematology; hematologic malignancies; natural compounds; bone marrow failures; tranfusion medicine
The mechanism by which hematological malignancies such as leukemia, lymphoma, and myeloma develop and proliferate in vivo is not yet fully understood. However, the possibility of eradicating cancer cells not only through allogeneic hematopoietic stem cell transplantation but also single-molecule targeted therapy, such as with CAR-T cells, suggests that the immune system, including innate and adaptive immunity, plays an important role in the development and pathophysiology of hematological malignancies. The involvement of immunological mechanisms has also been suggested in benign hematological disorders such as acquired aplastic anemia, paroxysmal nocturnal hemochromatosis, immune thrombocytopenia, thrombotic microangiopathy, and hemolytic anemia. In addition, hematological abnormalities associated with immunological dysregulation have also been noted in infectious diseases such as COVID-19 and autoimmune diseases. Therefore, there is a close pathophysiological relationship between hematological disorders and the immune system, and elucidation of these molecular mechanisms will advance the diagnosis and treatment of benign and malignant hematologic diseases, infectious diseases, and autoimmune diseases. This Special Issue focuses on molecular immunology in hematology and specifically welcomes studies that elucidate molecular immunological mechanisms in the diagnosis and treatment of hematological disorders, in addition to other topics that are relevant to the Special Issue theme.
Prof. Dr. Akiyoshi Takami
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Functional genetics
- Genetically-engineered therapy
- Hematopoietic stem cell transplantation