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Special Issue "Toxicology Assessment of Nanoparticles and Emerging Pollutants on Cell Models and Living Organisms"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".

Deadline for manuscript submissions: 28 February 2022.

Special Issue Editors

Dr. Valeria De Matteis
E-Mail Website
Guest Editor
Department of Mathematics and Physics “Ennio De Giorgi”, University of Salento, Via Monteroni, c/o Campus Ecotekne, 73100 Lecce (LE), Italy
Interests: inorganic nanoparticles; nanotoxicology; cytotoxicity; drug delivery; cancer cells; nanoparticles synthesis
Special Issues and Collections in MDPI journals
Dr. Mariafrancesca Cascione
E-Mail Website
Guest Editor
Department of Mathematics and Physics “Ennio De Giorgi”, University of Salento, Via Monteroni, c/o Campus Ecotekne, 73100 Lecce (LE), Italy
Interests: cancer cells; atomic force microscopy; cell mechanical alteration
Special Issues and Collections in MDPI journals
Prof. Dr. Quaiser Saquib
E-Mail Website
Guest Editor
Department of Zoology, College of Sciences, King Saud University, Riyadh 11451, Saudi Arabia
Interests: cell biology; molecular toxicology; transcriptomics; genotoxicity; nanotoxicity

Special Issue Information

Dear Colleagues,

The wide use of nanoparticles in several fields due to their unique physicochemical properties has raised the problem of their toxicity. Despite their numerous advantages, many nano-scale inorganic materials are considered toxic due to the high surface-to-volume ratio that increases their interaction with biological systems. Therefore, it is crucial to study in detail the interaction mechanism of nanoparticles with different cellular compartments (plasma membrane, subcellular organelles, and nucleus). Furthermore, the distribution kinetics within living organisms and their possible accumulation in organs and tissues are also essential to outline a toxicological profile, specific for each kind of nanoparticle. Although several studies have already been carried out, the scientific community is working on the formulation of standard guidelines in order to regulate the use of nanoparticles in commercial products and for applications in nanomedicine (as therapeutic agents, drug carriers, or diagnostic agents). On the other side, in recent decades, emerging pollutants (new flame retardants, new phthalates, alternative bisphenols) have been used as additive chemicals in a several consumer products. Humans can be exposed to these pollutants through different routes, leading to their detection in bodily fluids. These harmful substances are linked to several human health ailments, e.g., disturbances in hormone levels, fecundability, neurodevelopment disorders, and adverse birth outcomes.

This Special Issue of the International Journal of Molecular Science entitled “Toxicology Assessment of Nanoparticles and Emerging Pollutants on Cell Models and Living Organisms” aims to understand the toxic effects of different kinds of nanoparticles and emerging pollutants on cells and living organisms investigating the underlying mechanisms, disturbances in the biochemical pathways, and toxicogenomic changes. In addition, new techniques able to functionalize the surface of nanoparticles to reduce their adverse effects in vitro and in vivo are investigated.

Dr. Valeria De Matteis
Dr. Mariafrancesca Cascione
Prof. Dr. Quaiser Saquib
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanoparticles
  • cytotoxicity
  • genotoxicity
  • nanomedicine
  • nanotoxicity
  • emerging pollutants
  • toxicogenomics
  • molecular toxicity
  • cell death

Published Papers

This special issue is now open for submission.
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