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Special Issue "Natural Organic Compounds: Cellular Pathways and Effects"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 31 August 2021.

Special Issue Editor

Prof. Dr. Clara Balsano
E-Mail Website
Guest Editor
MESVA Department, University of L’Aquila, L’Aquila 67100, Italy
Interests: metabolic syndrome; hepatocarcinoma; obesity; liver steatosis; transition biometas; HBV and HCV infective diseases

Special Issue Information

Dear Colleagues,

Natural organic compounds are essential for human life. Efforts are needed to understand the signaling pathways influenced by natural organic compounds, mainly because they have great potential for the treatment of a wide range of pathologies. A large number of studies indicate that a variety of natural compounds, such as curcumin, green tea, olive oil, oleuropein, folate, copper, selenium, and isoflavones show a wide range of anti-inflammatory, anti-oxidant, and anti-tumoral properties, via targeting a sequence of cellular and molecular pathways. Natural compounds further contribute to the prevention or treatment of various pathologies interacting with powerful molecules, such as microRNAs and exosomes. Finally, they also have important effects on mitochondria functions, which play an important role in the pathogenesis of many pathologies (e.g., cardiovascular, neurological, inflammatory, metabolic, and cancer diseases).

Natural organic compounds, because they target multiple molecules, enhance their efficacy through synergistic interactions, and are not associated with adverse effects, as many pharmacological agents are, have specific applications for the prevention and treatment of a large number of chronic diseases.

This Special Issue will be focalized on the targeting of organic natural compounds to the subcellular compartments, one of the most promising trends in modern molecular pharmacology.

Prof. Dr. Clara Balsano
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Natural compounds
  • Nutraceuticals
  • Intracellular pathways
  • Mitochondrial dysfunction
  • Metabolic, inflammatory, and stress alterations
  • Targeted therapy

Published Papers

This special issue is now open for submission.
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