Special Issue "Sodium Voltage-Operated Neural Channel Modulators in Peripheral Nervous System Disorders"
Deadline for manuscript submissions: closed (30 April 2021).
Sodium voltage-operated ion channels (NaV) are widely represented in the peripheral nervous system (PNS), being crucial for action potential generation. Modulators of NaV are attracting interest as potential therapeutic strategies for PNS disorders. They represent a valuable strategy for neuropathic pain management, gaining attention in the post “opioid crisis” era, which was strongly felt by healthcare professionals, in particular, in the US; moreover, NaV modulators are also attracting interest as neuroprotectants against axonal damage, in particular, when the underlying mechanism is axonal hyperexcitability. This Special Issue explores the applicability and usage of NaV modulators against PNS disorders, including but not limited to mechanical, metabolic, genetic, toxic, and dysimmune neuropathy.
Dr. Paola Alberti
Manuscript Submission Information
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- sodium voltage-operated neural ion channels
- peripheral nervous system
- neuropathic pain
- axonal damage
- sodium/calcium exchangers (NCX)