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Special Issue "Sodium Voltage-Operated Neural Channel Modulators in Peripheral Nervous System Disorders"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: closed (30 April 2021).

Special Issue Editor

Dr. Paola Alberti
E-Mail Website
Guest Editor
School of Medicine and Surgery ,University of Milano-Bicocca,italiy
Interests: neuropathy, ion channels, voltage gated ion channels, pain, chemotherapy

Special Issue Information

Dear Colleagues,

Sodium voltage-operated ion channels (NaV) are widely represented in the peripheral nervous system (PNS), being crucial for action potential generation. Modulators of NaV are attracting interest as potential therapeutic strategies for PNS disorders. They represent a valuable strategy for neuropathic pain management, gaining attention in the post “opioid crisis” era, which was strongly felt by healthcare professionals, in particular, in the US; moreover, NaV modulators are also attracting interest as neuroprotectants against axonal damage, in particular, when the underlying mechanism is axonal hyperexcitability. This Special Issue explores the applicability and usage of NaV modulators against PNS disorders, including but not limited to mechanical, metabolic, genetic, toxic, and dysimmune neuropathy.

Dr. Paola Alberti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • sodium voltage-operated neural ion channels
  • peripheral nervous system
  • neuropathic pain
  • axonal damage
  • sodium/calcium exchangers (NCX)
  • neuropathy
  • hyperexcitability

Published Papers

There is no accepted submissions to this special issue at this moment.
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