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Special Issue "Molecular Mechanisms of Neural Circuit Development and Regeneration 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editors

Prof. Dr. Lieve Moons
E-Mail Website
Guest Editor
Neural Circuit Development and Regeneration Research Group, Department of Biology, University of Leuven, Leuven, Belgium
Interests: neurodegeneration; axonal regeneration; neuroinflammation; retina; optic nerve; mouse; teleost fish; mitochondria; intraneuronal transport and communication
Special Issues and Collections in MDPI journals
Dr. Lies De Groef
E-Mail Website
Guest Editor
Neural Circuit Development and Regeneration Research Group, Department of Biology, University of Leuven, Leuven, Belgium
Interests: neurodegeneration; neuroinflammation; retina; optic nerve; mouse; protein aggregation; Parkinson’s disease; extracellular vesicles; intercellular transport and communication
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue follows the publication of the first edition on the “Molecular Mechanisms of Neural Circuit Development and Regeneration”, which presented 13 high-quality papers.

The human brain has one hundred billion neurons, each neuron connected to ten thousand other neurons. Understanding how these neural circuits are formed and what is needed for them to be repaired is one of the biggest challenges in modern science. Studies in different animal models have helped to unravel the principles of neural circuit formation yet have also pointed out striking differences in the regenerative capacity of the central nervous system (CNS) among species. Further insights into the gene networks, molecular players, and (sub)cellular entities responsible for neural circuit formation are still urgently needed and may propel the search for neuroprotective and reparative strategies for treating neurodevelopmental and neurodegenerative conditions.

An intriguing question with respect to neural circuit formation is how this process is being orchestrated in the developing CNS, and whether this developmental program can be used to regenerate adult neural circuits. We especially encourage submissions that address the common or differential molecular and cellular mechanisms involved in neurodevelopment and regeneration, as well as other comparative research focusing on, for example, animal model organisms with different regenerative capacities, and CNS versus peripheral nervous system repair.

The Special Issue is open to original papers, reviews, and other forms of scientific communication that increase our fundamental understanding of neural circuit development and regeneration.

Prof. Dr. Lieve Moons
Dr. Lies De Groef
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Axonal development/regeneration
  • Axonal branching
  • Neurogenesis
  • Stem cells
  • Neuroprotection
  • Neural circuit formation
  • Neural circuit recovery
  • Regenerative potential
  • Central nervous system
  • Peripheral nervous system
  • Comparative research
  • Molecular mechanisms
  • Cellular mechanisms

Published Papers

This special issue is now open for submission.
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