Special Issue "Neuronal Control of Locomotion"
Deadline for manuscript submissions: closed (30 April 2021).
Interests: Motor Control; Neuroscience; Locomotion; Central Pattern Generation; Proprioception; Reflexes
One of the main areas of Neuroscience research is understanding how the nervous system generates and controls movement. Research that aims to understand locomotion, defined as the movement of an organism from one place to another, has been one of the main areas contributing to this understanding. During locomotion, patterned and rhythmic contractions of multiple muscles underlie the coordinated movement of the body or limbs to provide posture and propulsion. These patterned contractions of muscles are controlled by the activities of motor neuron pools located within the central nervous system (CNS). It is generally accepted that at least some aspects of this patterned motor neuron activation are controlled by the action of a pre-motor network of interneurons within CNS, the central pattern generator (CPG). Moreover, the activity of the CPG is constantly modified by the sensory feedback from the periphery that provides the CPG with the information regarding the terrain, the body, and equilibrium. Despite the large volume of information that we have accumulated over the last century, core aspects of the neuronal mechanisms that control locomotion remain obscure. Advances in developmental and molecular biology, combined with new neuroscience methods for recording locomotor activity, have provided us with new opportunities to better our understanding.
The purpose of this Special Issue is to highlight different aspects of the neuronal control of locomotion using different approaches, including molecular biology, neuroscience, biomechanics, and computational approaches, on different model systems.
Assoc. Prof. Turgay Akay
Manuscript Submission Information
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- molecular biology
- gene delivery
- motion analysis
- in vivo electrophysiology
- in vitro electrophysiology
- central pattern generators
- sensory feedback