Special Issue "Neuroinflammation: From Molecular Mechanisms to Therapeutic Perspectives"
Deadline for manuscript submissions: 31 May 2021.
Interests: Hepatic encephalopathy; neuroinflammation; cognitive impairment; cerebellum; hippocampus; motor coordination; cytokines; glutamate receptors; GABA transporters; microbiota metabolits
Diseases that involve the nervous system and different neuropsychiatric syndromes, including those simply associated with aging, are currently one of the great concerns in global health. There is no doubt that neuroinflammation is involved to a greater or lesser degree in most brain diseases, whether chronic, neurodegenerative, or involving acute brain damage, for a multitude of different causes. This means that knowing the different mechanisms involved in the appearance of neuroinflammation would be very useful to understand the mechanisms of the different alterations in brain function. Once the mechanisms are known in detail, a wide field of possible therapeutic targets will be opened, based on neuroinflammation processes, which undoubtedly must be developed to establish therapeutic strategies that can prevent or improve a multitude of brain diseases and symptoms, such as cognitive impairment (from mild to more severe), memory loss, motor impairment, mood, and even coma and death. This is necessary today in order to improve general health, given the high incidence of mental illnesses that affect the quality of life of many people, either due to illness or simply associated with aging.
The relationship between neuroinflammation and alterations in neurotransmission are still unknown, and it would be very important to advance the knowledge of these mechanisms in order to expand the therapeutic possibilities, since altered neurotransmission is the main basis of alterations in brain function, and therefore the cause of different neurological disorders.
The objective of this Special Issue is to update the knowledge about the mechanisms of neuroinflammation in different circumstances and the therapeutic implications that it entails—not only based on the mechanisms that lead to neuroinflammation, but also on how it interferes with brain mechanisms (mainly neurotransmission) to alter brain function.
Prof. Dr. Marta Llansola
Manuscript Submission Information
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- Neurological disorders
- Molecular mechanisms
- Neurotransmitter receptors
- Signal transduction
- Therapeutic targets