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Special Issue "Neuroinflammation in Parkinson's Disease"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editor

Dr. Juliet M. Taylor
E-Mail Website
Guest Editor
Department of Pharmacology and Therapeutics, The University of Melbourne, Victoria 3010, Australia
Interests: neuroinflammation; type-I interferons; Parkinson’s disease; microglia; Alzheimer’s disease

Special Issue Information

Dear Colleagues,

Parkinson’s disease (PD) is a chronic neurodegenerative disease characterised by motor dysfunction due to a loss of dopaminergic neurons.  It is considered a multifactorial disorder promoted by both genetic defects and exposure to environmental factors influencing disease progression. Recent clinical, epidemiological and experimental evidence has implicated neuroinflammation in contributing to the neuronal cell death and progression of PD. This chronic neuroinflammatory response within the central nervous system is driven by the resident immune cells of the brain, the microglia and astrocytes; however, recent studies have identified an important contribution of the peripheral immune response to the CNS pathology in PD. This aim of this Special Issue is to gain a greater understanding of the complex molecular mechanisms that lead to chronic neuroinflammation in PD and how these contribute to the dopaminergic cell death in the brain. Both high-quality original research and review articles are welcome discussing the following: neuroinflammation in cell-based and animal models of PD, microglia and astrocytes in PD, the gut–brain axis, the role of the peripheral immune response, and the development of therapeutic strategies targeting neuroinflammation.

Dr. Juliet M. Taylor
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • parkinson’s disease
  • neurodegenerative
  • neuroinflammation
  • microglia
  • astrocytes
  • gut-brain axis
  • alpha-synuclein
  • dopamine

Published Papers

This special issue is now open for submission.
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