Special Issue "Neuroinflammation in Parkinson's Disease"
Deadline for manuscript submissions: 30 September 2021.
Parkinson’s disease (PD) is a chronic neurodegenerative disease characterised by motor dysfunction due to a loss of dopaminergic neurons. It is considered a multifactorial disorder promoted by both genetic defects and exposure to environmental factors influencing disease progression. Recent clinical, epidemiological and experimental evidence has implicated neuroinflammation in contributing to the neuronal cell death and progression of PD. This chronic neuroinflammatory response within the central nervous system is driven by the resident immune cells of the brain, the microglia and astrocytes; however, recent studies have identified an important contribution of the peripheral immune response to the CNS pathology in PD. This aim of this Special Issue is to gain a greater understanding of the complex molecular mechanisms that lead to chronic neuroinflammation in PD and how these contribute to the dopaminergic cell death in the brain. Both high-quality original research and review articles are welcome discussing the following: neuroinflammation in cell-based and animal models of PD, microglia and astrocytes in PD, the gut–brain axis, the role of the peripheral immune response, and the development of therapeutic strategies targeting neuroinflammation.
Dr. Juliet M. Taylor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- parkinson’s disease
- gut-brain axis