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Special Issue "Omics Strategies in Male Reproduction"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Genetics and Genomics".

Deadline for manuscript submissions: 30 April 2022.

Special Issue Editors

Prof. Dr. Monika Frączek
E-Mail Website
Guest Editor
Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland
Interests: male infertility; spermatogenesis; sperm physiology and pathology; environmental factors; semen quality; seminal biomarkers; male genital tract inflammation/infection; microbiota of male genital tract; oxidative stress; sperm mitochondria; sperm chromatin integrity; sperm epigenetics; seminal proteom; seminal metabolom
Dr. Marzena Skrzypczak-Zielińska
E-Mail Website
Guest Editor
Institute of Human Genetics, Polish Academy of Sciences, Poznan, Poland
Interests: seminal microbiota composition in health and disease; male infertility metagenomic research; high throughput techniques and omics data in male infertility studies

Special Issue Information

Dear Colleagues,

Male infertility has become a social and civilization disease, and started to be a serious challenge for public health. Due to limited predictive value of standard semen analysis in assessing the ability of the sperm to fertilize the oocyte, highly specialized scientific and diagnostic tools are needed to look for new non-invasive seminal biomarkers of male infertility, both in natural and assisted reproduction. Molecular research in sperm biology and male infertility is a very dynamic field of science. Omics-based studies using high-throughput technologies offer great potential for understanding the regulatory mechanisms that drive gene and protein expression during sperm development, detecting gene-environment or host-pathogen interactions underlying normal and pathological spermatogenesis. This research strategy is crucial to gain enough knowledge to envisage future diagnostic and therapeutic procedures to improve human reproductive health. 

The idea of the Special Issue is to advance the research on male infertility and the molecular background of spermatogenesis. Both original manuscripts and reviews discussing the genome, transcriptome, epigenome, proteome and metabolome data related to male factor fertility/infertility in humans and animal models are very welcome.

Prof. Dr. Monika Frączek
Dr. Marzena Skrzypczak-Zielińska
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • male infertility
  • normal and pathological spermatogenesis
  • seminal biomarkers
  • sperm chromatin
  • genomics
  • transcriptomics
  • epigenomics
  • proteomics
  • metabolomics
  • microbiome
  • 16S rRNA gene sequencing
  • miRNA
  • microarrays
  • next generation sequencing
  • cell in vitro studies
  • animal model studies

Published Papers

This special issue is now open for submission.
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