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Special Issue "Molecular Mechanisms of Human Oogenesis and Early Embryogenesis"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 30 December 2021.

Special Issue Editor

Dr. Jan Tesarik
E-Mail Website
Guest Editor
MARGen Clinic, Molecular Assisted Reproducion and Genetics, 18006 Granada, Spain
Interests: molecular mechanisms of spermatogenesis; molecular mechanisms of oogenesis; molecular mechanisms of fertilization; molecular mechanisms of early embryogenesis; molecular markers of male infertility; molecular markers of female infertility; molecular mechanisms of miscarriage; molecular control of reproductive function; translational molecular medicine in infertility management
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

This special issue treats with the relationships between molecular events taking place during human oogenesis and the molecular control of the early events during human preimplantation development. The main interest is focused on the human species, with possible applications in the development of novel diagnostic and therapeutical approaches to human infertility management.

Given the fact that the early embryogenesis in species with the late embryonic gene activtion are largely dependent on molecules transmitted by the oocyte, this issue intends to cover, mainly but not exclusively, the repertoire of molecules stored during oogenesis in the oocytes, and their respective roles in the regulation of the early postfertilization events in embryonic development. The principal questions are how these molecules are involved in epigenetic events in early human embryos, to what extent they can repair both sperm and oocyte genetic damage, their relationship with the patient’s age and hormonal status, and the possible ways of therapeutic actions in cases of abnormalities.

The rationale of this special issue is that a thorough knowledge of the molecular mechanisms involved in the above events should be used as a guide for specific diagnostic and therapeutic procedures used in cases of human infertility.

Dr. Jan Tesarik
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • oogenesis
  • early embryogenesis
  • oocyte activation
  • markers of oocyte and embryo quality
  • suitable animal models
  • human infertility diagnosis and treatment

Published Papers

This special issue is now open for submission.
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