Special Issue "Neurobiological Mechanisms of Orofacial Chronic Pain"
Deadline for manuscript submissions: 31 May 2021.
Interests: ion channels; pain; electrophysiology; nociceptors; transient receptor potential ion channels, trigeminal ganglia
Special Issues and Collections in MDPI journals
Interests: somatosensation; in vivo calcium imaging; voltage sensing imaging; in vivo second messengers imaging; network activity of primary sensory neuron (dorsal root ganglia & trigeminal ganglia) and surrounding cells; electrophysiologic recording; chronic pain; chronic itch; signaling molecules for nociception
Orofacial pain arises not only from skin and mucosa but also from deep tissues such as masticatory muscles and joints. A wide variety of etiologies, such as tissue inflammation and nerve injury, leads to chronic pain that is often resistant to conventional therapies. Multiple idiopathic chronic pain conditions in orofacial regions, such as temporomandibular joint disorders (TMD), burning mouth syndrome (BMS), or atypical odontalgia, are very difficult to diagnose and properly treat. In spite of great advances over the last few decades, the neurobiological mechanisms underlying chronic pain conditions of the orofacial area are still not clearly understood.
This Special Issue is devoted to better understanding the neurobiological mechanisms of orofacial pain. The scope includes but is not limited to peripheral and central mechanisms of orofacial pain, neural pathways or signaling mechanisms in sensory ganglia or brain, genetic and epigenetic mechanisms, and neural and synaptic plasticity in preclinical models. The Special Issue also welcomes translational studies and clinical studies involving human subjects or functional MRI associated with orofacial pain. A more detailed understanding of the unique neurobiology of orofacial pain should help us develop novel methods and therapeutics for better treating orofacial persistent pain.
Prof. Dr. Man-Kyo Chung
Dr. Yu Shin Kim
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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- orofacial pain
- trigeminal system
- neural circuit of orofacial neuropathy
- chronic pain
- preclinical study
- human study