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Special Issue "Oxidative Stress: Focusing on New Therapeutic Approaches and Biochemical Markers"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 30 April 2021.

Special Issue Editors

Prof. Dr. Daniela Impellizzeri
Website
Guest Editor
Department of Chemical biological,pharmaceutical and environmental sciences, Università degli Studi di Messina, Messina, Italy
Interests: inflammation; oxidative stress; biochemistry; pharmacology; molecular biology
Special Issues and Collections in MDPI journals
Dr. Roberta Fusco
Website
Guest Editor
Department of Chemical biological,pharmaceutical and environmental sciences, Università degli Studi di Messina, Messina, Italy
Interests: Biochemistry; Molecular Biology; Inflammation; Oxidative stress; Pharmacology
Dr. Rosalba Siracusa
Website
Guest Editor
Department of Chemical biological,pharmaceutical and environmental sciences, Università degli Studi di Messina, Messina, Italy
Interests: Biochemistry; Molecular Biology; Inflammation; Oxidative stress; Pathology; Pharmacology

Special Issue Information

Dear Colleagues,

A free radical can be defined as any molecular species capable of independent existence that contains an unpaired electron in an atomic orbital. Many abiotic stresses induce the overproduction of reactive oxygen species (ROS) in humans and animals. As highly reactive and toxic species, they cause damage to DNA, proteins, carbohydrates, and lipids, thus leading to oxidative stress. This oxidative stress induces damage to cells and tissues, resulting in a large number of diseases. Several compounds with antioxidant properties could neutralize the effects of ROS and prevent the development of many inflammatory pathologies. A number of scientific studies report the varied health benefits of antioxidant supplementation in processes such as inflammation, stress, aging, apoptosis and neurological diseases.

This Special Issue will focus on the role of the antioxidant therapy on different human diseases and possible molecular pathways involved. Moreover, the Special Issue will welcome reviews and original studies providing evidence of the effect of antioxidants factors wellbeing.

Prof. Dr. Daniela Impellizzeri
Dr. Roberta Fusco
Dr. Rosalba Siracusa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antioxidant
  • biochemical marker
  • one health
  • wellbeing
  • nutrition
  • animal model
  • in vitro study

Published Papers

This special issue is now open for submission, see below for planned papers.

Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title 1: Psychological resilience in older people - associations with increased inflammation and oxidative stress and the development of chronic medical conditions

Authors: L.T.Majnarić; T.Kurevija; M.Volarić

Abstract: The term resilience, which has been present in science for almost half a century, stands for the capacity of some system needed to overcome the amount of disturbance from the environment in order to avoid it change to another stable state. In medicine, the concept of resilience means ability of dealing with daily stress and disturbance to our homeostasis with the intention of protecting it from disturbance. With aging it comes to a loss of resilience, which makes the organism more sensitive to environmental impacts and more susceptible to changes. Mental disturbances and the lack of psychological resilience in older people are frequent and potentiated with many social and environmental factors, along with the subjective perception of decreasing health. Distinctly from as it may be in younger age groups, mental and physical medical conditions in older people are closely associated with each other, sharing common mechanisms and potentiating each other`s development. Increased inflammation and oxidative stress have been recognized as the main driving mechanisms in the development of aging diseases. This essay aims to reveal, through a translational approach, molecular mechanisms of emotional distress and low psychological resilience in older individuals as driving mechanisms for the accelerated development of chronic aging diseases, and to systematize the available information sources on the strategies for mitigation of low resilience in order to prevent chronic diseases.

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