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Special Issue "Biological Role of Oxidative Stress in Inflammatory Diseases"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 15 July 2021.

Special Issue Editors

Prof. Dr. Sara Franceschelli

Guest Editor
Medicine and Health Science School, Chieti, Italy
Interests: nutrition; cellular biology; oxidative stress; cardiovascular disease; endogenous antioxidant enzymes; bioactive vegetable; molecules
Prof. Lorenza Speranza
Website
Guest Editor
Department of Medicine and Science of Aging, University G. D’Annunzio, 66100 Chieti, Italy
Interests: oxidative stress, nutrition; cellular biology; disease; antioxidant; bioactive vegetable; molecules; endogenous antioxidant enzymes; vegetable food; nitric oxide; inflammation and cardiovascular disease
Special Issues and Collections in MDPI journals
Dr. Chiara D’Angelo
Website
Assistant Guest Editor
Dept Medical, Oral and Biotechnological Sciences University “G. D’Annunzio” Chieti-Pescara, Italy
Interests: inflammation; gel electrophoresis; agarose gel electrophoresis; neurodegeneration; neurodegenerative diseases

Special Issue Information

Dear Colleagues,

The imbalance between reactive oxidant species and endogenous antioxidant defense mechanisms promotes the development of a condition of oxidative stress, which has considerable biological consequences. Increasing evidence is proving that oxidative stress plays a pivotal role in the development and progression of inflammation, and thus contributes to the pathophysiology of a number of diseases, such as cancer, cardiovascular diseases, diabetes, and neurodegenerative processes.

Oxidant species influence all phases of the inflammatory response, including the release by damaged tissues of molecules acting as endogenous danger signals. Their sensing by innate immune receptors from the Toll-like (TLRs) and the NOD-like (NLRs) families leads to activation of signaling pathways promoting the adaptive cellular response to such signals.

While we tend to describe oxidative stress simply as harmful for the human body, it is also true that it is exploited as a therapeutic approach to treat clinical conditions such as cancer, with a certain degree of clinical success.

We can conclude that oxidative stress, although being one of the major injuries to individuals' wellness and health, can also be exploited as a treatment tool.

Therefore, correlations between oxidative stress, inflammation, and disease should be carefully investigated in order to better understand the etiopathogenesis of diseases and to develop ad hoc future treatments.

Prof. Dr. Sara Franceschelli
Prof. Lorenza Speranza
Guest Editors
Dr. Chiara D’Angelo
Assistant Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

This special issue is now open for submission.
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