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Special Issue "Recent Applications of PLGA-Based Nanoparticles in Drug Delivery"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 31 October 2021.

Special Issue Editor

Dr. Viktória Varga
E-Mail Website
Guest Editor
Department of Physical Chemistry and Materials Science, University of Szeged, Szeged, Hungary
Interests: colloids; self-assembly; drug-delivery; thin films; serum albumin; kynurenic acid; PLGA; atomic force microscopy; isotherm titration calorimetry

Special Issue Information

Dear Colleagues,

The new drug delivery strategies provide major advances over conventional medicine in the delivery of different drugs in a controlled and targeted manner with enhanced bioavailability and thus reduced side effects. Among the different polymer-based drug delivery systems, poly (lactic-co-glycolic acid) (PLGA), the synthetic block copolymer of lactic acid and glycolic acid, is one of the leading carriers in modern biomedical investigations both in local, long-term, and targeted drug delivery. Their popularity arises from their favorable physicochemical properties, their versatility towards modification, their biocompatibility, and their ability to improve the distribution and bioavailability of pharmaceutics. PLGA also plays an important role in the development of controlled and targeted drug delivery systems in the form of nanoparticles, microcapsules, and matrices. However, there are some drawbacks in the application of PLGA such as its low encapsulation efficiency and limited release of certain drugs.

The Special Issue aims to present novel PLGA-based treatment strategies, including encapsulation and transport of pharmaceuticals, in the treatment of various diseases and disorders. Topics may also include any aspects of the design, characterization, and functionalization of PLGA-containing delivery systems. State-of-the-art research on promising systems with both in vitro and in vivo analysis and controlled release with potential pre-clinical application is also welcome. We are looking forward to receiving manuscripts focused on the most recent advances in the field of PLGA-based drug delivery systems.

Dr. Viktória Varga
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • PLGA
  • poly (lactic-co-glycolic acid)
  • drug delivery
  • encapsulation
  • sustained release
  • targeted therapy

Published Papers

This special issue is now open for submission.
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