Special Issue "Proteostasis and Proteasome Inhibitors 2.0"
Deadline for manuscript submissions: 28 February 2021.
Interests: natural products chemistry; bioactive small molecules; anti-inflammatory drugs; pro-apoptotic drugs; endoplasmic reticulum stress; proteostasis
Special Issues and Collections in MDPI journals
Special Issue in International Journal of Molecular Sciences: Proteostasis and Proteasome Inhibitors
Special Issue in Pharmaceuticals: Terpenes – Pharmaceutics and Biotechnology
Special Issue in International Journal of Molecular Sciences: Dual Targeting as a Strategy to Counteract Chronic Diseases
The function of proteins is largely affected by their tridimensional structure, nevertheless incorrect folding of proteins is an inevitable problem that is present in all eukaryotic organelles. Misfolded proteins often present reduced or even absent activity and can be the basis of several proteinopathies, including neurodegenerative diseases or even lysosomal storage disease. To prevent the aggregation of misfolded proteins, eukaryotic cells have evolved robust pathways that are often interconnected with compartmental protein quality control. These pathways detect misfolded proteins and action refolding into functional proteins using chaperones, sequestering them in large inclusions pathway proteins, small heat shock chaperone, or degrading them through the ubiquitin-proteasome system or autophagy. This special issue will be dedicated to all aspects of proteostasis, protein quality control pathways, and proteasome inhibitors.
Prof. Dr. David Pereira
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Proteasome inhibitors
- Lisosome storage diseases
- Neurodegenerative diseases