Special Issue "RNA-Binding Proteins and Their Emerging Roles in Cancer"
Deadline for manuscript submissions: 28 February 2021.
Interests: RNA-Binding Proteins and Cancer
Interests: RNA-DNA Damage Response and Cancer
Interests: RNA/DNA Secondary Structures; Genomic Instability and Human Disease
The human genome encodes more than 1500 RNA-binding proteins (RBPs), and the number is expected to increase with the addition of RBPs that contain non-canonical RNA binding motifs. These proteins are at the center of transcriptional and post-transcriptional regulation of gene expression and play a central role in all four highly regulated interconnected pathways, namely: transcriptional responses, RNA–DNA damage responses, and DNA repair and apoptosis. Mutations in several RBPs have been linked to cancers, and therefore, RBPs and their associated pathways are potential drug targets. Increasing evidence from research in the past decade highlights the intricate interplay between RNA metabolism, RNA binding proteins, and genome stability in human health and disease. The proposed issue will broadly cover the following topics:
- RNA-binding proteins in RNA metabolism;
- RNA-binding proteins in RNA–DNA damage response;
- RNA-binding proteins in cancer-associated instability;
- New technologies to study RNA-binding proteins and RNA/DNA secondary structures;
- Unresolved RNA/DNA secondary structures and genomic instability.
Dr. John Murphy
Dr. Kalpana Surendranath
Dr. Radhakrishnan Kanagaraj
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- gene expression
- RNA splicing
- RNA editing
- non-coding RNA
- RNA–DNA damage
- DNA repair
- genome instability