Special Issue "Female Reproduction: The Link between Basic Ovarian Events and the Microenvironment of the Oocyte"
Deadline for manuscript submissions: 31 October 2021.
Female fertility potential is based on the development of ovarian follicles, and ovarian pathologies constitute one of the main causes of infertility. The revelation of new targets involved in ovarian pathophysiology represents a significant scientific challenge. The fertilization of the mammalian oocyte requires tight interactions between the oocyte-cumulus extracellular matrix and spermatozoa. The expression of several essential components of the extracellular matrix has been confirmed in the mammalian ovarian follicles, and the impaired expression of their genes led to serious cumulus defects resulting in mice infertility. There is still an incomplete understanding of the specific changes that occur in the follicles leading to the modification of oocytes’ capacity to develop to the blastocyst stage. The elucidation of novel/unexplored signalling pathways that function as central regulators of cellular protein synthesis and metabolism in the oocyte microenvironment are of great interest.
Research focused on determining the follicular microenvironment produced by ovarian cells and its molecular characterisation could lead to the understanding of several fertility problems.
This Special Issue welcomes original research and review papers that aim to provide up-to-date reports on the link between basic ovarian events and the microenvironment of the oocyte.
Prof. Dr. Eva Nagyova
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- female fertility
- ovarian pathologies
- follicular microenvironment