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Special Issue "Skin Histopathology: Focused on Ageing and Cancer"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 31 March 2021.

Special Issue Editors

Dr. Lukas Lacina
Guest Editor
Dpt. of Dermatovenerology, First Faculty of Medicine, Charles University U nemocnice 2, 128 00 Praha 2 Czech Republic
Interests: skin; cancer; skin disease; cell biology;
Special Issues and Collections in MDPI journals
Dr. Michal Kolář
Website1 Website2
Guest Editor
Institute of Molecular Genetics, Czech Academy of Sciences
Interests: genetics; genomics; transcriptomics; epigenetics; molecular biology; cancer; development

Special Issue Information

Dear Colleagues,

Skin represents the largest organ of the human body with numerous physiological functions. Notably, the skin as a barrier is life-long exposed to the outer environment, and it is facing all its potentially damaging effects. Therefore human skin suffers from both either intrinsic ageing, but also extrinsic factors enhancing this process.

Ageing is accompanied by a plethora of phenotypic changes in the structure of cutaneous cells and extracellular matrix, but also by their functional changes.  As a result, aged skin is associated with higher susceptibility to poor self-renewal and healing, with increased risk of development of various dermatoses, and it is also prone to develop skin cancer.

In this Special Issue, we wish to broaden our understanding to skin ageing, highlight recent hot topics in structural and functional changes of skin and also unveil molecular mechanisms leading to these changes.

We aim to promote knowledge and understanding of the various facets related to skin health and disease with emphasis on various aspects of cutaneous ageing-related pathologies because it can strengthen our diagnostic and treatment strategies and potentially prevent or even reverse skin ageing.

Dr. Lukas Lacina
Dr. Michal Kolář
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • epidermis
  • dermis
  • senescence-associated secretory phenotype
  • ageing
  • dermatoporosis
  • healing
  • cancer
  • photodamage
  • stem cell
  • renewal

Published Papers

This special issue is now open for submission.
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