Special Issue "Space Omics: Adaptive Gene Expression Changes after Exposure to Spaceflight and Simulated Extraterrestrial Environments"
Deadline for manuscript submissions: 30 September 2021.
Interests: Gene redundancy (nucleolin mutants) contribution to suboptimal environments adaptation; altered gravity/radiation simulation & hardware; Spaceflight countermeasures (light, sucrose…)
In recent years, multiple model systems, including for humans, have been exposed to microgravity environments, either real (spaceflight) or simulated. Transcriptomic studies, using microarray or, more recently, sequencing (RNAseq) techniques, are by far the most frequently performed. An important effort for data sharing and harmonization has been undertaken by the project called GeneLab, under the leadership of NASA and the participation of laboratories from different countries. GeneLab organizes datasets in the Data Repository, analyses data using the Analysis Platform, and creates collaborative projects using the Collaborative Workspace. NASA GeneLab is organized into different analysis working groups (AWGs) supported internationally by other consortiums, such as ISSOP (https://issop.space/) and the Space Omics Topical Team funded by ESA.
Recent reviews, with important contributions from European scientists (at The Biology of Spaceflight compendium at Cell), have been presented to the scientific community regarding the current opportunities for space-omics research that discuss how to give space biology research the opportunity to meet molecular biology gold standards. This Special Issue aims to go further into describing a subtle, but general, stress response, usually linked to mitochondrial function, as a common response observed across all kingdoms of life so far, usually observed in synergy with the molecular level adaptation to suboptimal environments, such as those observed in spaceflight and microgravity simulation experiments. State of the art multi-omics-based manuscripts are welcome, with a particular emphasis on describing past, present, and future contributions of European molecular biology scientists to the international landscape in space omics research.
Dr. Raúl Herranz on behalf of the Space Omics Topical Team core members
Dr. Raúl Herranz
Manuscript Submission Information
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- space biology
- system biology
- spatial transcriptomics
- astronaut health monitoring
- life support and model systems
- spaceflight hardware