Topical Collection "Stress, Immunity, and Tissue Microenvironment"
Interests: gene and cell therapies; mesenchymal stem cells; innate immunity; respiratory diseases; neurodegenerative diseases; biomarkers
Special Issues and Collections in MDPI journals
The inflammatory response is activated by a complex network of exogenous and endogenous warning signals that bring about either repair and homeostasis or disease. The tissue microenvironment is essential in dictating these alternative responses by engendering cellular pathways of stress, such as those related to the endoplasmic reticulum and the mitochondria. The hyperthermic response (i.e., fever) seems to be the link among different cell types and molecular stressors, indicating that other inflammation-related events might be responsible for alterations in the microenvironment. This topic collection aims to unveil the composite roles of molecular stress responses in cancer, chronic inflammatory, and autoimmune diseases. It is undoubtful that an in-depth knowledge of these pathways will indicate how to bring forth both novel biomarkers and therapeutic approaches for these important diseases.
Assoc. Prof. Massimo Conese
Prof. Dr. Arcangelo Liso
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