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Special Issue "Synaptic Plasticity and Diseases"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 31 July 2021.

Special Issue Editor

Dr. Hiroki Toyoda
E-Mail Website
Guest Editor
Department of Oral Physiology, Osaka University Graduate School of Dentistry, Suita 565-0871, Japan
Interests: synaptic transmission; synaptic plasticity; ion channel; electrophysiology; cortex; trigeminal system

Special Issue Information

Dear Colleagues,

Synaptic plasticity is a basic process in the brain that allows humans and animals to adapt to changes in their environment and is considered the neural basis of learning and memory as well as brain disorders including Alzheimer's disease, Parkinson's disease, autism, schizophrenia, mental retardation, chronic pain and drug addiction. Long-term potentiation (LTP) and long-term depression (LTD) are the most intensively studied forms of activity-dependent synaptic plasticity. It is now clear that that LTP and LTD are involved in many physiological functions and are linked to various brain disorders. An understanding of the cellular and molecular mechanisms of synaptic plasticity could aid the development of effective treatments for brain disorders. This Special Issue will be of interest to basic and clinical researchers involved in studies that focus on synaptic plasticity and diseases.

Dr. Hiroki Toyoda
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Synaptic plasticity
  • Long-term potentiation
  • Long-term depression
  • Learning
  • Memory
  • Brain disorders

Published Papers

This special issue is now open for submission.
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