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Special Issue "TRPM Channels"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 1 July 2021.

Special Issue Editors

Dr. Balazs Istvan Toth
Website
Guest Editor
Laboratory of Molecular and Cellular Physiology, Department of Physiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
Prof. Thomas Voets
Website
Guest Editor
Laboratory of Ion Channel Research (VIB-KU Leuven Center for Brain & Disease Research) Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium

Special Issue Information

Dear Colleagues,

The Melastatin (TRPM) subfamily of the fascinating Transient Receptor Potential (TRP) ion channels forms a structurally and functionally diverse group of eight close relatives of cation channels. They are characterized by diverse gating stimuli, including changes in environmental temperature, osmolarity, ADP-ribose or intra- and extracellular ions. They function as thermosensors, gatekeepers of cellular ion homeostasis, or regulators of secretory functions, inflammatory processes and redox signaling. Some of them possess a unique double identity, simultaneously functioning as ion channels and enzymes (“chanzymes”).

TRPM channels are widely studied in the sensory system, in various immune cells, as well as in epithelial barriers, but they are virtually expressed by every cell-types of the human body. Intense research of the past two decades advanced a lot in their understanding and in the last years we gained a deeper insight into their molecular structure. However, in spite of our rapidly growing knowledge, there are still several mysteries in this intriguing group of ion channels. This Special Issue provides a forum for summarizing our current knowledge and presenting selected chapters of actual research targeting any aspect of these exciting members of TRP channels. 

Dr. Balazs Istvan Toth
Prof. Thomas Voets
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

This special issue is now open for submission.
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