Journal Browser

Journal Browser

Special Issue "Thermophilic and Hyperthermophilic Microbes and Enzymes 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: 31 October 2021.

Special Issue Editors

Dr. Giuseppe Manco
E-Mail Website
Guest Editor
Istituto di Biochimica e Biologia Cellulare, Naples, Italy
Interests: structure and function of thermostable enzymes; human enzymes and disease; proteomics; bioremediation and detoxification; biosensors; functional materials
Special Issues and Collections in MDPI journals
Dr. Yannick J. Bomble
E-Mail Website
Guest Editor
National Renewable Energy Laboratory, Golden, CO, USA
Interests: biomass deconstruction and conversion; enzyme engineering; cell free production of biochemicals
Special Issues and Collections in MDPI journals
Dr. Elena Porzio
E-Mail Website
Guest Editor
Institute of Biochemistry and Cell Biology (IBBC), National Research Council (CNR), Via Pietro Castellino 111, 80131 Naples, Italy
Interests: biochemistry & molecular biology; thermostable enzymes; archaeal proteins; bioremediation; protein engineering (in vitro molecular evolution); high throughput screening; antimicrobials

Special Issue Information

Dear Colleagues,

Thermophilic and hyperthermophilic microbes represent a fascinating class of microorganisms, not only because of their resilience to thrive at elevated temperatures and in harsh environments, but also because of the enzymes that they harbor. These microorganisms fall mainly in the bacteria and archaea domains, and exist in many habitats including hot springs, hydrothermal vents, or volcanic ash sediments, among others. These habitats all exhibit thermophilic or hyperthermophilic temperatures, but can also be acidic, alkaline, or contain high levels of salts. In order to thrive in such harsh environments, these microorganisms have evolved robust enzymes that are able to function at peak activity in these harsh conditions. These microorganisms represent a rich source of enzymes with an increased stability, which are purposely modified by protein engineering and can excel in harsh industrial conditions, making them especially appealing for biotechnological applications. Sometimes, they display promiscous activities that represent a peculiar basis for evolution. Bioprospecting for enzymes in these microbes has gained popularity in the last two decades, as they also represent ideal templates and strategies for reengineering essential but less stable enzymes, catalyzing reactions that do not exist in thermophiles.

This Special Issue encourages original research articles, perspectives, and reviews on the topic of thermophilic and hyperthermophilic microbes and enzymes. Topics of interest include, but are not limited to, the following:

  • Bioprospecting
  • Enzyme characterization
  • Microbial phenotypes
  • Novel metabolic pathways
  • Novel metabolic enzymes
  • Bioremediation
  • Enzyme evolution and engineering
  • Proteomics approach
  • Microbial ecology
  • Microbial consortia

Related Special issue "Thermophilic and Hyperthermophilic Microbes and Enzymes" and previous papers:

Altered Cofactor Preference of Thermostable StDAPDH by a Single Mutation at K159

Structural and Functional Characterization of New SsoPox Variant Points to the Dimer Interface as a Driver for the Increase in Promiscuous Paraoxonase Activity

Metabolic Adaptation to Sulfur of Hyperthermophilic Palaeococcus pacificus DY20341T from Deep-Sea Hydrothermal Sediments

Occurrence of Thermophilic Microorganisms in Different Full Scale Biogas Plants

DING Proteins Extend to the Extremophilic World

Effect of Cultivation Parameters on Fermentation and Hydrogen Production in the Phylum Thermotogae

O6-alkylguanine-DNA Alkyltransferases in Microbes Living on the Edge: From Stability to Applicability

Dr. Giuseppe Manco
Dr. Yannick J. Bomble
Dr. Elena Porzio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

This special issue is now open for submission.
Back to TopTop