Dear Colleagues,

Chronic alcohol abuse is a significant cause of cirrhosis and liver failure in adults worldwide. Alcoholic liver disease (ALD) is a pathological process characterized by progressive liver damage that leads to steatosis, steatohepatitis, fibrosis, and finally cirrhosis. Eventually, cirrhosis may progress to hepatic decompensation and hepatocellular cancer. Therefore, ALD is an important cause of morbidity and mortality. There is an urgent need to develop efficient strategies for patients with ALD.

Although remarkable achievements has been made in the mechanisms of ALD, there is still no effective therapy for ALD. Recently, there has been growing studies in elucidating the role of foods and food components as suppressors of alcohol–induced oxidative stress and liver damage.

This Special Issue would like to deepen the relationship between food components and preventive effect for ALD. The studies using in vitro and/or in vivo models are welcome.

Prof. Dr. Akiko Kojima-Yuasa
Guest Editor

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• Alcoholic liver disease
• Hepatitis
• Liver fibrosis
• Food components
• Hepatocyte
• Hepatic stellate cells
• Reactive oxygen species
• Alcohol dehydrogenase
• Cytochrome P450 2E1