Special Issue "Cellular and Molecular Mechanisms of Bone Metastasis"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 June 2016).
Interests: bone metastasis from breast carcinoma; hepatocyte growth factor; Met receptor; hypoxia; microenvironment; epithelial-mesenchymal transition; transcriptional regulation
Special Issues and Collections in MDPI journals
Metastasis to the skeleton is the principal cause of death of patients with breast and prostate cancer, and multiple myeloma. The molecular pathogenesis of bone metastasis represents one of the leading aspects considered by the Molecular Medicine, because of the importance of deepening the biology of the process and for personalized therapy. The multidisciplinary approach of study is strongly desirable due to the multiple facets of the bone metastasis process, which are supported by genetic and epigenetic mechanisms, through systemic signals and local physical and biological stimuli. The bone metastatic process may be investigated from different points of view, including the pathology of cellular events, nanotechnology and structural/biological engineering, as well as the molecular biology of invasiveness, of mesenchymal-epithelial transition and its reversion, and of transcription factor regulation.
This Special Issue, “Cellular and Molecular Mechanisms of Bone Metastasis”, will cover a selection of recent research topics and current review articles in the field of invasiveness and bone metastasis.
Prof. Dr. Maria Alfonsina Desiderio
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- bone metastasis
- breast carcinoma
- prostate carcinoma
- multiple myeloma
- growth factors
- epithelial-mesenchymal transition
- epigenetic mechanisms