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Special Issue "Cancer and Neurodegenerative Diseases: What Is the Link?"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".

Deadline for manuscript submissions: 31 January 2022.

Special Issue Editors

Dr. Angela Ostuni
E-Mail Website
Guest Editor
Department of Sciences, University of Basilicata, 85100 Potenza, Italy
Interests: cell biology; biochemistry; biomarkers; transcriptome; cancer; ABC transporters; metabolism; recombinant proteins
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Faustino Bisaccia
E-Mail Website
Guest Editor
Department of Sciences, University of Basilicata, 85100 Potenza, Italy
Interests: purification of protein carriers; artificial membranes; transport mechanism; amino acid sequence; transmembrane topography of transport proteins; oligomeric structure
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Even though the association is not always clear, and the results have often been contradictory, many epidemiological studies have linked cancer and neurodegenerative disorders.

Cancer and neurodegeneration are two biological processes which, despite working in two opposite directions, i.e., uncontrolled cell proliferation and cellular degeneration, share several genes and biological pathways involved in mitochondrial dysfunction, ROS production, oxidative stress, inflammation, metabolic deregulation, DNA damage, and aberrant cell cycle activation. Aging plays an important role in the link between the two disorders.

This Special Issue invites researchers to exploit the crosstalk between the two disorders through an in-depth investigation into the cellular and molecular mechanisms of the overlapping pathways, with particular attention to considering aspects such as mutational analysis, the role of secretome, and the activation of the immune system. Understanding the mechanisms underlying these interactions might lead to designing therapeutic approaches that can guarantee benefits in cancer surveillance as well as neuroprotection.

Dr. Angela Ostuni
Prof. Dr. Faustino Bisaccia
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cancer
  • neurodegenerative diseases
  • polymorphisms
  • miRNAs signature
  • mitochondria
  • aging
  • secretome
  • cytoskeleton
  • antitumor immunity

Published Papers

This special issue is now open for submission.
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