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Special Issue "Cellular and Molecular Biology in Autoimmune Disease"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 31 August 2021.

Special Issue Editors

Prof. Dr. Cristina Belizna
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Guest Editor
Vascular and Coagulation Department, University Hospital Angers, 49100 Angers, France
Interests: antiphospholipid syndrome; OMICS; immune; autoimmune; rheumatology
Special Issues and Collections in MDPI journals
Prof. Dr. Pier Luigi Meroni
E-Mail Website
Guest Editor
Immunorheumatology Research Laboratory, IRCCS Istituto Auxologico Italiano, 20145 Milano, Italy
Interests: autoimmunity; autoimmune disease; cellular biology; molecular biology; cellular pathways; self-tolerance; molecular mechanisms; pathogenesis; therapy
Special Issues and Collections in MDPI journals
Prof. Jaume Alijotas-Reig
E-Mail
Guest Editor
Systemic Autoimmune Disease Unit, Department of Internal Medicine, Vall d’Hebron University Hospital, Barcelona, Spain
Department of Medicine, Universitat Autonòma, Barcelona, Spai
Interests: autoimmunity; autoimmune disease; cellular biology; molecular biology; cellular pathways; self-tolerance; molecular mechanisms; pathogenesis; therapy
Prof. Omar Latino
E-Mail
Guest Editor
Autoimmune and Thrombophilic Disorders Department, Hospital Carlos G. Durand, Buenos Aires, Argentina
Hospital Carlos G. Durand, Buenos Aires, Argentina
Interests: autoimmunity; autoimmune disease; cellular biology; molecular biology; cellular pathways; self-tolerance; molecular mechanisms; pathogenesis; therapy

Special Issue Information

Dear Colleagues,

We are pleased to kindly invite you to contribute with your research to the special Issue: Cellular and Molecular Biology in Autoimmune Disease.

As autoimmune disease remain a major medical concern and the mechanisms responsible for their pathogenesis are still incompletely understood, new insights in this field are needed. Various cellular, molecular, and physiological mechanisms have been suggested as potential triggers for the loss of self-tolerance, which make immune cells unable to distinguish among “self” and “non-self” antigens. Cellular mechanisms coupled with various mechanisms at the molecular level initiate dysregulated intercellular communication and are involved in the pathogenesis of autoimmune disease. Both innate and acquired immune system have been determined to be involved at the molecular level.

New data into genetic susceptibility suggest that environmental triggers could act via cellular pathways containing disease-associated polymorphisms. The full and deep understanding of these mechanisms will allow an adapted therapy. Recent treatments are expected to simultaneously and specifically target several pathways in autoimmunity. Due to the heterogeneity of autoimmune mechanisms, the knowledge in this area are expected to lead to a personalized molecular medicine approach in the field of autoimmune disease. Your data are expected to contribute to new insights in this unravelled field and you are very welcome to join us.

Prof. Dr. Cristina Belizna
Prof. Dr. Pier Luigi Meroni
Prof. Jaume Alijotas-Reig
Prof. Omar Latino
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • autoimmunity
  • autoimmune disease
  • cellular biology
  • molecular biology
  • cellular pathways
  • self-tolerance
  • molecular mechanisms
  • pathogenesis
  • therapy
  • personalized molecular medicine

Published Papers

This special issue is now open for submission.
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