Special Issue "Epigenetic Connections between the Gene Regulatory Network and Chromatin Dynamics"
Deadline for manuscript submissions: closed (30 November 2020).
Interests: chromatin; epigenetics; development
Cells in tissues have different phenotypes and functions determined by lineage-specific and signal-responsive gene expression patterns. Activation or repression of gene transcription is facilitated by epigenetic mechanisms controlling the accessibility of DNA in nuclear chromatin. Transcription factors and histone- and DNA-modifying enzymes cooperate in gene regulatory networks that act on individual genes or genomic domains in the nucleus and can maintain gene expression patterns through cell divisions. This Special Issue focuses on gene regulation mechanisms involving transcription factors, epigenetic modifying and chromatin remodelling complexes acting at specific genomic loci or altering chromosomal dynamics. A better understanding of how cell types and cell states are defined will advance further insight into cell differentiation and cell function in normal tissues and in disease.
Potential topics include, but are not limited to:
- Gene Regulatory Network
- Chromosome / chromatin dynamics
- 3D genome and nuclear architecture
- Epigenome and transcriptome
Dr. Sari Pennings
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- gene regulation
- gene activation and repression
- histone modification
- DNA methylation
- non-coding RNA
- chromosome dynamics