Special Issue "Biomarkers in Inflammatory and Chronic Degenerative Diseases"
Deadline for manuscript submissions: 31 December 2021.
Interests: heart failure; sympathetic nervous system; ageing; beta-adrenergic receptors; biomarkers; cardiac remodeling; frailty
Special Issues and Collections in MDPI journals
Interests: biomarkers of allergic disorders; autoimmune diseases and primary immunodeficiencies
Interests: pulmonary hypertension; right heart function; right heart failure
Inflammatory and chronic degenerative diseases are the leading causes of death and disability worldwide, and their burden is accelerating, advancing across every country. These diseases significantly affect the quality of life of patients and caregivers, as well as constitute a huge expense for health systems.
The field of biomarker research is globally expanding to improve the management of patients with inflammatory and chronic pathologies, with a specific focus on disease progression and response to therapies. Molecular biology and molecular medicine support even more the evaluation of physiological and pathogenic processes or therapeutic effectiveness.
Accordingly, their employment is being implemented in the clinical practice for early diagnosis and for the development of novel therapeutic targets to better prevent and manage inflammatory and chronic diseases. Further, biomarkers may be useful in monitoring the effect of actions aimed at ameliorating patients’ management and at optimizing the allocation of resources.
One of the critical points of these degenerative conditions is represented by the limits in the early identification of disease reactivation, and even diagnostic criteria are burdened with the complexity of real-world patients (i.e., high number of comorbidities). In this context, the application of biomarkers is extremely relevant in order to implement diagnosis accuracy, specificity, and sensitivity.
In recent decades, several underlying molecular mechanisms of chronic diseases have been recognized, including low-grade inflammation, allowing the identification of novel therapeutic approaches and biomarkers. Thus, this Special Issue in IJMS will cover a selection of recent investigations and current review articles focused on the identification and application of biomarkers in the management of inflammatory and chronic degenerative diseases, such as cardiovascular, immunological, musculoskeletal, and neurodegenerative disorders. We kindly invite researchers to submit manuscripts regarding novel signaling pathways with relevant implication in the pathophysiology of inflammatory and chronic diseases, which may have a direct potential impact in the management of these patients.
Prof. Dr. Giuseppe Rengo
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- chronic degenerative diseases
- low grade inflammation
- inflammatory diseases
- signaling pathways
- molecular mechanisms