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Special Issue "Target Dysfunctional Inflammation in Cystic Fibrosis Airway 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 31 March 2022.

Special Issue Editor

Dr. Valérie Urbach
E-Mail Website
Guest Editor
INSERM, U1151, Institut Necker Enfants Malades, 75993 Paris, France
Interests: cystic fibrosis; ion transport; lipid mediators of inflammation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

A major cause of morbidity and mortality in patients with cystic fibrosis (CF) is the exaggerated and dysfunctional airway inflammation, which contributes to irreversible airway destruction and fibrosis. Inflammation in the CF airways can occur very early in CF, independently of bacterial infection. This unresolved inflammation contributes to disease progression and determines life expectancy. This Special Issue will give an overview of the recent discovery of key immune processes involved in CF airway disease, the impact of CFTR dysfunction and CFTR modulators therapy on the CF inflammatory phenotype, and the therapeutic perspectives to target airway inflammation in patients with CF.

Dr. Valérie Urbach
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cystic fibrosis airway
  • inflammation
  • early inflammation in CF
  • resolution of inflammation
  • lipoxins
  • resolvins
  • leucotrienes
  • airway surface liquid pH
  • cannabinoid
  • protease
  • elastase
  • cathepsin
  • non-steroidal anti-inflammatory molecules

Published Papers

This special issue is now open for submission.
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