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Special Issue "Dental Pulp Stem Cells: Unveiling Their Multifaceted Therapeutic Potential II"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".

Deadline for manuscript submissions: 31 October 2021.

Special Issue Editors

Dr. Carnevale Gianluca
E-Mail Website
Guest Editor
Department of Surgery, Medicine, Dentistry and Morphological Sciences with interest in Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, 41125 Modena, Italy
Interests: dental pulp stem cells; mesenchymal cells; regenerative medicine
Special Issues and Collections in MDPI journals
Dr. Alessandra Pisciotta
E-Mail Website
Guest Editor
Department of Surgery, Medicine, Dentistry and Morphological Sciences with interest in Transplant, Oncology and Regenerative Medicine, University of Modena and Reggio Emilia, 41125 Modena, Italy
Interests: dental pulp stem cells; regenerative potential; human stem cells isolated from amniotic fluid
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Dental pulp is a loose connective tissue entrapped within the pulp chamber of the teeth and is a reservoir of adult stem cells characterized by self-renewal, a high proliferation rate, and broad differentiation potential, features to be attributed to the peculiar embryological origin from the neural crest, which is currently considered the fourth germ layer. Since their discovery in the early 2000s, the differentiation potential of these stem cells has been extensively investigated, demonstrating their plasticity of application to several animal models of tissue injury, including bone, nerve, muscle, and cartilage defects, often in association with the use of different types of biomaterials/scaffolds. A further notable feature of these stem cells is represented by their immunomodulatory and anti-inflammatory capabilities, which are currently under investigation and might provide insights into their potential application to allogeneic transplants under immunosuppression-free regimens, as well as to the treatment of immune and inflammatory-related diseases. In this Special Issue, we invite researchers to contribute original research articles, as well as review articles, that elucidate novel insights regarding the potential of dental pulp stem cells for multiple therapeutic applications. These include, but are not limited, to the fields mentioned in the keywords.

Dr. Carnevale Gianluca
Dr. Alessandra Pisciotta
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular mechanisms of immunomodulation
  • secretome’s role in tumor growth/progression
  • miRNA signature
  • modulation of angiogenesis
  • dynamic culture systems for large-scale expansion
  • organ on a chip and microfluidics
  • effects of bioactive molecules and growth factors
  • interactions with different biomaterials for soft and hard tissue regeneration
  • stem cell potential for neurodegenerative diseases

Related Special Issue

Published Papers

This special issue is now open for submission.
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