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Special Issue "Impact of Diet on Cancer Therapy"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 31 August 2021.

Special Issue Editor

Prof. Dr. Ahmed Bettaieb
E-Mail Website
Guest Editor
Department of Nutrition, The University of Tennessee-Knoxville, Knoxville, TN 37996-1920, USA
Interests: metabolic diseases; obesity; type 2 diabetes; protein tyrosine phosphatases; protein kinases; hydrolases
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Pharmacological approaches to combat cancer have been met with limited success despite intensive investments in their development. Over the past decade, the importance of dietary factors and caloric intake in modulating cancer risk has become increasingly apparent. Investigations targeting the contribution of caloric intake regarding cancer progression and development have revealed significant findings. Caloric restriction has demonstrated potential against various cancers through modulation of key signaling pathways important for various aspects of carcinogenesis including, inflammation, cell cycle, angiogenesis, autophagy, and apoptotic signaling pathways. Additionally, numerous natural dietary compounds including several calorie restriction mimetics have been investigated for their potential as either therapeutic or preventive agents against several types of cancer. However, further efforts towards a comprehensive understanding of the role of dietary factors in cancer biology, the metabolic and physiological consequences, as well as, their associated clinical outcomes are needed. Therefore, this issue will focus on the overall dietary effects on carcinogenesis and how alternative approaches may be potentiated as adjunct, first line and preventive care options.

Prof. Dr. Ahmed Bettaieb
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • pharmacological approaches
  • dietary factors
  • caloric intake
  • metabolism
  • cancer
  • calorie restriction
  • carcinogenesis
  • metabolic and physiological consequences

Published Papers

This special issue is now open for submission.
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