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Special Issue "Diet-Microbiota and Host Interactions in Intestinal Health and Inflammation 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".

Deadline for manuscript submissions: 28 February 2022.

Special Issue Editor

Dr. Silvia Melgar
E-Mail Website
Guest Editor
APC Microbiome Ireland, University College Cork, Cork, Ireland
Interests: novel therapies for inflammatory gastrointestinal tract
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In the last decade, the collected evidence indicates that the microbiota modulates the metabolic status, educates the host’s intestinal immune system, and protects the host against invading pathogens. Concomitantly, environmental factors such as diet have also been shown to shape the microbiota, thereby modulating the immune response and ultimately directing the health status of each individual. Therefore, disruptions in any of these three elements or their interactions have been linked to the development and progression of a number of intestinal inflammatory conditions including inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), celiac disease, colorectal cancer, etc. While Westernized diets rich in fat/sugar, low in fibers, and containing dietary additives such as emulsifiers have been linked to the development and progression of these disorders, other diets such as Mediterranean, ketogenic, and low-FODMAP, as well as dietary fiber supplementation, can potentially serve as treatment options due to their impact on the microbiota and on the host.

In this Special Issue, we welcome original research papers, reviews, short communications, and discussion papers addressing mechanisms regulated by diet, microbiota, and host interactions, revealing new cellular and immunological pathways targeted by bacteria and bacterial metabolites, diets, diet components, dietary additives, dietary fibers, etc. associated with intestinal health and disease.

Dr. Silvia Melgar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • diet
  • dietary additives and components
  • dietary fibers
  • westernized diet
  • intestinal inflammation
  • cancer
  • Immune system
  • epithelial cells
  • gut microbiota
  • bacterial metabolites

Published Papers

This special issue is now open for submission.
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