Special Issue "Inflammation and Resolution in Endometriosis: From Science to Clinic"
Deadline for manuscript submissions: 31 August 2021.
Endometriosis is a hormonal dependant benign disease that affects up to 12% of women during reproductive life. In the past decade, the number of patients with endometriosis has continued to increase and its aetiology has not been clearly elucidated. It is considered a chronic inflammatory and proliferative disease whose onset and development involves immunologic mechanisms.
Basic science research has also described the inflammation associated with the disease and its correlation to dysmenorrhoea and chronic pelvic pain.
A local burst of prostaglandins induced by macrophages and mesothelial cells surrounding the endometriotic implants are involved in the process of chronic pain.
Describing the molecular mechanisms of inflammation and resolution of inflammation in endometriosis lesions will improve the ability to develop targeted pain reducing substances.
The special issue focuses on the molecular description of inflammatory and pro resolving molecular aspects and their possible implications in the management of the endometriosis associated pain.
Dr. Pedro-Antonio Regidor
Manuscript Submission Information
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- chronic pain
- resolution of inflammation