Special Issue "Cell Fate Decisions in Neural Development"
Deadline for manuscript submissions: 31 August 2021.
Interests: neural crest; neural tube; roof plate, somite; mesoderm; myogenesis; peripheral nervous system; cell migration; epithelial-to mesenchymal transition; neuronal specification; developmental neurobiology; developmental biology; avian embryo
The large diversity of cell types that set up the complexity of the central and peripheral branches of the nervous system originates from small groups of progenitors during embryonic development. The combinatorial expression of specific genes that define a given cell identity is controlled by interactions between signaling proteins, transcription factors, and epigenetic mechanisms.
Recent advances in methodologies addressing these diverse levels of regulation have opened new opportunities to answer classical questions of when and how progenitors adopt their final identity and turn into functionally distinct cells. It is the combination between this emerging, large-scale basis of knowledge, and established gain and loss of function approaches that will impact the field in the coming years.
The scope of this collection will cover cellular and molecular mechanisms leading to the acquisition of specific identities of progenitors issued from the neural tube and neural crest in vertebrate embryos. This includes interactions at the signaling, transcriptional, and translational levels of regulation. Studies addressing these questions that implement both in vivo models as well as in vitro approaches based on embryonic stem cells or induced pluripotent stem cells will be welcome.
Prof. Dr. Chaya Kalcheim
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- cell specification
- cell lineage
- cell-cell interactions
- neural tube
- neural crest
- neuronal development
- glial development
- gene regulatory networks
- gene editing
- pattern formation