Special Issue "Genetic Alterations in Tumors"
Deadline for manuscript submissions: 31 January 2022.
2. Institute of Medical Genetics, Academic Hospital of Udine, Udine, Italy
Interests: medical Genetics; genetic diseases; cancer genetics
With advances in high-throughput technologies like next-generation sequencing, remarkable progress has been made in understanding genetic events that define the identity of tumors and characterize cancer development and metastasis. Integrative analysis of genomic alterations, signaling, and other molecular changes in tumor cells have allowed not only biomarker discovery, but also the identification of novel therapeutic targets. Personalized cancer therapy based on genetic status has shown great promise for the improvement of patient outcomes. However, many challenges remain, including tumor heterogeneity and therapeutic resistance arising from genetic mutations as compensatory mechanisms. It is also now clear that there are interplays between the genome and epigenome of tumor cells, adding another layer of complexity in our understanding of cancer.
In this Special Issue, we welcome reviews, original research articles, and short communications that focus on advances related to identifying genetic events that improve cancer diagnosis, the development of targeted therapy, combating resistance, as well as genetic events changing the epigenomic landscape of tumor cells.
Prof. Dr. Giuseppe Damante
Dr. Rebecca Chin
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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