Special Issue "New Advance in Compositional Genome Evolution"
Deadline for manuscript submissions: closed (30 September 2021).
Nucleotide composition, i.e., not only the primary DNA sequence but also the proportion of AT versus GC, is a crucial factor driving important genomic features like gene density, DNA methylation, DNA mutations, DNA replication timing, chromatin structure, proportion and types of transposons, nucleosome formation potential, and many more. However, despite the still increasing number of sequenced genomes, it is still unclear why mammalian and avian genomes are AT/GC heterogeneous, whereas genomes of lower vertebrates are AT/GC homogenous.
In this Special Issue, we aim to integrate the latest results from prokaryotes and eukaryotes, plants and animals, unicellular and multicellular organisms, and above all vertebrates to assess the currently relevant viewpoints of the compositional genome evolution. Namely, we aim to analyse GC-related structural as well as functional traits regarding neutral evolutionary processes and potential roles of selection in genomes and their transposons.
Dr. Radka Symonova
Manuscript Submission Information
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- AT/GC evolution in prokaryotes
- AT/GC evolution in eukaryotes
- AT/GC evolution of eukaryotic transposons (active, inactive, DNA transposons, retrotransposons)
- Role of selection in GC biology
- Levels of gene expression and GC content