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Special Issue "Gut Hormone: From Molecular Mechanism to Clinical Aspects 2021"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".

Deadline for manuscript submissions: 31 August 2021.

Special Issue Editor

Prof. Dr. Bunzo Matsuura
E-Mail Website
Guest Editor
Department of Lifestyle-related Medicine and Endocrinology, Graduate School of Medicine, Ehime University, Shitsukawa 454, Toon, Ehime 791-0295, Japan
Interests: gut hormone; thyroid disease; obesity; diabetes mellitus; nonalcoholic fatty liver disease
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Gut hormones are closely related to lifestyle and lifestyle-related disorders. Gut hormones affect appetite, gastrointestinal motility, digestion, absorption and metabolism, and hence abnormalities of gut hormones cause malnutrition, metabolic syndrome and GI disorders. Gastrin and insulin have cell proliferation activity, and therefore abnormality of these hormones or hormone receptors affects development or progression of several cancers, for example pancreatic cancer and colorectal cancer.

Understanding of the molecular basis of hormone binding and activation of receptors provides important insights into the active conformation of such receptors, providing critical information helpful for the design and refinement of receptor-active drugs. The family of guanine nucleotide-binding protein (G protein)-coupled receptors that includes receptors for many gut hormones are demonstrated as clinically useful pharmacological targets.

This topic was covered in 2019 and was very well received. This time, we decided to cover it again.

Papers related to any aspects of biochemistry, molecular biology, pharmacology, physiology, and pathology will be considered for this Special Issue. The pure clinical reports may not be accepted.

Prof. Dr. Bunzo Matsuura
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Appetite
  • Motility
  • Digestion
  • Absorption
  • Metabolism
  • Microbiome
  • Immunity
  • Cell proliferation
  • Neuroendocrine tumor (NET)
  • Functional dyspepsia
  • Irritable bowel syndrome

Published Papers

This special issue is now open for submission.
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