Special Issue "The Role of Hydrolases in Biology and Xenobiotics Metabolism"
Deadline for manuscript submissions: closed (31 January 2021).
Interests: epoxide hydrolase; oxylipin; enzyme inhibition; inflammation; neuropathic pain; metabolic diseases
Chemical exposure can profoundly affect our health. Some exposures are voluntary (food, drugs), and some involuntary (environmental contaminants). Nevertheless, the metabolism of these chemicals is essential for their detoxification, elimination, and sometimes, their activation. Of the numerous enzymes involved in the metabolism of xenobiotics, this Special Issue will concentrate on hydrolases.
Hydrolases are part of a heterogeneous group of enzymes that catalyze bond cleavages by reactions with water. Beside some well documented roles in the metabolism of foreign chemicals, recent new findings demonstrate biological roles for hydrolases, implicating them in the regulation of cardiovascular diseases, inflammatory responses, and neurologic diseases among others.
This Special Issue will focus on both basic science and translational research of the biological roles of hydrolases in mammals, and also in their role in the metabolism of toxins and natural products.
Dr. Christophe Morisseau
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- epoxide hydrolase
- cardio-vascular diseases